RSV Disease

Our RSV research generates real-world evidence on the epidemiology, burden, health care utilization, clinical outcomes, and prevention of RSV disease across pediatric and adult populations, with particular focus on high-risk groups, severe respiratory illness, and associated cardiorespiratory complications.

Respiratory Infections

RSV disease remains an important public health concern because it can cause substantial respiratory illness and health care utilization across both pediatric and adult populations, particularly among infants, older adults, and individuals with underlying health conditions.

Key Publications

Bourdeau M, Vadlamudi NK, Bastien N, Embree J, Halperin SA, Jadavji T, Kazmi K, Langley JM, Lebel MH, Le Saux N, Moore D, Morris SK, Pernica JM, Robinson J, Sadarangani M, Bettinger JA, Papenburg J; Canadian Immunization Monitoring Program Active (IMPACT) Investigators. Pediatric RSV-Associated Hospitalizations Before and During the COVID-19 Pandemic. JAMA Netw Open. 2023 Oct 2;6(10):e2336863. doi: 10.1001/jamanetworkopen.2023.36863. PMID: 37792376; PMCID: PMC10551765.
Vadlamudi NK, Gomes K, Chow E, Bourdeau M, Embree J, Halperin SA, Jadavji T, Kazmi K, Langley JM, Le Saux N, Moore D, Morris SK, Pernica JM, Robinson J, Sadarangani M, Bettinger JA; Canadian Immunization Monitoring Program Active (IMPACT) Members. Healthcare costs and resource utilization for acute respiratory syncytial virus pediatric hospitalizations in Canada: a population-based study. Lancet Reg Health Am. 2025 Oct 6;51:101257. doi: 10.1016/j.lana.2025.101257. PMID: 41323549; PMCID: PMC12664583.
Bourdeau M, Vadlamudi NK, Bancej C, Bastien N, Embree J, Halperin S, Hudgin A, Jadavji T, Kazmi K, Langley JM, Lebel M, Le Saux N, Moore DL, Morris S, Pernica J, Robinson J, Sadarangani M, Bettinger JA, Papenburg J. 2613. Pediatric respiratory syncytial virus hospitalizations, 2017 to 2022, the Canadian Immunization Monitoring Program Active (IMPACT). Open Forum Infect Dis. 2023 Nov 27;10(Suppl 2):ofad500.2226. doi: 10.1093/ofid/ofad500.2226. PMCID: PMC10677744.
Yang J, Smith SM, Jiao T, Smith K, Shirley DA, Veena V, Iovine NM, Vadlamudi NK. P-672. Comparative Risk of Major Adverse Cardiovascular Events Following RSV versus Influenza Hospitalization in the United States: A MarketScan Database Retrospective Cohort Study. Open Forum Infect Dis. 2026 Jan 11;13(Suppl 1):ofaf695.885. doi: 10.1093/ofid/ofaf695.885. PMCID: PMC12792668.