Pneumococcal disease research is a key area of our work, encompassing studies of epidemiology, disease burden, healthcare utilization, economic impact, vaccine effectiveness, and real-world evidence to support prevention strategies and policy decision-making.
Respiratory Infection
Pneumococcal Disease
Despite the availability of vaccines, pneumococcal disease continues to place a substantial burden on patients, healthcare systems, and public health programs.
Key Publications
- Vadlamudi NK, Chen A, Marra F. Impact of the 13-Valent Pneumococcal Conjugate Vaccine Among Adults: A Systematic Review and Meta-analysis. Clin Infect Dis. 2019 Jun 18;69(1):34-49. doi: 10.1093/cid/ciy872. PMID: 30312379.
- Vadlamudi NK, Parhar K, Altre Malana KL, Kang A, Marra F. Immunogenicity and safety of the 13-valent pneumococcal conjugate vaccine compared to 23-valent pneumococcal polysaccharide in immunocompetent adults: A systematic review and meta-analysis. Vaccine. 2019 Feb 14;37(8):1021-1029. doi: 10.1016/j.vaccine.2019.01.014. Epub 2019 Jan 23. PMID: 30685252.
- Marra F, Vadlamudi NK. Efficacy and Safety of the Pneumococcal Conjugate-13 Valent Vaccine in Adults. Aging Dis. 2019 Apr 1;10(2):404-418. doi: 10.14336/AD.2018.0512. PMID: 31011485; PMCID: PMC6457056.
- Ramos B, Vadlamudi NK, Han C, Sadarangani M. Future immunisation strategies to prevent Streptococcus pneumoniae infections in children and adults. Lancet Infect Dis. 2025 Jun;25(6):e330-e344. doi: 10.1016/S1473-3099(24)00740-0. Epub 2025 Mar 17. PMID: 40112854.
- Delara M, Vadlamudi NK, Sadarangani M. Strategies to Prevent Early and Late-Onset Group B Streptococcal Infection via Interventions in Pregnancy. Pathogens. 2023 Feb 1;12(2):229. doi: 10.3390/pathogens12020229. PMID: 36839501; PMCID: PMC9959229.