Our vaccine research generates evidence on vaccine effectiveness, safety, immunogenicity, and disease impact, including studies of pneumococcal conjugate vaccines in adults and children, vaccine effects on pneumococcal disease epidemiology, and recombinant herpes zoster vaccine in immunocompromised populations.
effectiveness & safety of vaccines
Vaccines
Vaccine studies provide critical evidence on vaccine effectiveness, safety, immunogenicity, and population-level impact, supporting evidence-based immunization policies and prevention strategies for vulnerable populations.
Key Publications
- Vadlamudi NK, Chen A, Marra F. Impact of the 13-Valent Pneumococcal Conjugate Vaccine Among Adults: A Systematic Review and Meta-analysis. Clin Infect Dis. 2019 Jun 18;69(1):34-49. doi: 10.1093/cid/ciy872. PMID: 30312379.
- Vadlamudi NK, Parhar K, Altre Malana KL, Kang A, Marra F. Immunogenicity and safety of the 13-valent pneumococcal conjugate vaccine compared to 23-valent pneumococcal polysaccharide in immunocompetent adults: A systematic review and meta-analysis. Vaccine. 2019 Feb 14;37(8):1021-1029. doi: 10.1016/j.vaccine.2019.01.014. Epub 2019 Jan 23. PMID: 30685252.
- Marra F, Yip M, Cragg JJ, Vadlamudi NK. Systematic review and meta-analysis of recombinant herpes zoster vaccine in immunocompromised populations. PLoS One. 2024 Nov 25;19(11):e0313889. doi: 10.1371/journal.pone.0313889. PMID: 39585863; PMCID: PMC11588208.
- Vadlamudi NK, Saatchi A, Patrick DM, Rose C, Sadatsafavi M, Marra F. Impact of the 13-valent pneumococcal conjugate vaccine on acute otitis media and acute sinusitis epidemiology in British Columbia, Canada. J Antimicrob Chemother. 2021 Aug 12;76(9):2419-2427. doi: 10.1093/jac/dkab167. PMID: 34021757.
- Vadlamudi NK, Patrick DM, Hoang L, Sadarangani M, Marra F. Incidence of invasive pneumococcal disease after introduction of the 13-valent conjugate pneumococcal vaccine in British Columbia: A retrospective cohort study. PLoS One. 2020 Sep 30;15(9):e0239848. doi: 10.1371/journal.pone.0239848. PMID: 32997698; PMCID: PMC7526878.